Author: sophia
Over the past 20 years been a sharp increase in the incidence of HPV. Genital warts are one of the most common sexually transmitted infections (STIs). They meet 3 times more likely than genital herpes, Giving primacy only chlamydia and gonorrhea. DNA virus papillomavirus man was found in 6 of men and 10 of women without any clinical manifestations of disease.
Infection of adults usually occurs from sexual partners who have symptomatic or subclinical manifestations of the disease. Patients and their partners, therefore, require careful clinical and modern and laboratory evaluation. Most often, genital warts occur in women and men aged 16-30 years. The incubation period ranges from 1 to 9 months (30 of patients an average of 2-3 months).
Genital warts are most often localized on the external genitals, the anus and sometimes on the mucous membrane of the mouth. The spectrum of clinical manifestations of this infection is very wide. They can occur without any signs of abnormalities of the surface epithelium and revealed only by careful inspection using special diagnostic optical devices (colposcopy, uretrotsistoskopiya) Or histologically tissue removed, but may well diagnosed even when viewed with the naked eye.
The clinical course of disease depends on the genotype, the place of its introduction into the skin or mucous membrane of the genital organs, the total reactivity (immune) systems.
Genital warts look like small growths, which are located on an unmodified basis in the form of a thin filament or short legs, and resemble small warts (in the form of raspberries, cauliflower, or cock\'s comb). Depending on the location, they can be solid or intense red, while maceration - whitish, sometimes they erode and emit fetid fluid.
In men, genital warts usually are located on the ground who are exposed to traumatic injury during sexual intercourse: bridle, coronal sulcus, the head, the foreskin of the penis. They also occur on the trunk of the penis and scrotum, where there are often multiple. Sometimes warts affect men the urethra, situated throughout the urethra, where they can be totally asymptomatic or condition the picture of chronic urethritis.
In women, warts show on the external genitals, the urethra, vagina, the cervix, about 20 - around the anus and the perineum. Often they are located only on the lips and inside the urethra to the wall, also celebrated their deeper location in the urethra. In the latter case they cause a phenomenon stubbornly flowing urethritis and cystitis.
Warts on the cervix occurs in approximately 6 of women, they may be isolated or sochetatsya with genital warts vagina. On the cervix warts, merge to form large plaques pale yellow or white. Very often, such patients are diagnosed with - 'Cervical erosion of unknown origin 'and unsuccessfully treated for a long time this disease.
Numerous studies have conclusively established that the cause of many diseases of the cervix, The squamous epithelium of other genital organs and the anus (called dysplasia or intraepithelial neoplasia) is papillomavirus people. This is evidenced by the following data:
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* In 40 of women infection of the cervixCaused by HPV infection 16th or 18th type within 2 years is transformed into a malignant dysplasia or carcinoma in situ.
* Human Papilloma Virus 16th-and 18th-type are found in 90 of women with squamous cell carcinoma or epithelial dysplasia of the cervix. This relationship, although somewhat less frequently observed in malignant tumors of the vagina, penis and anus.
The most accurate method of diagnosis of HPV is the molecular DNA diagnostics. With this advanced method can not only accurately identify the presence of HPVBut it opredelitt vidoprinadlezhnost (genotype) of the virus. That is, only using DNA research to get answers to pressing medical issue, whether the identified species HPV to infection with a high or low risk of crustaceans, which significantly affects the patient\'s treatment selection. DNA-diagnostics available definition of the virus even when asymptomatic, oligosymptomatic forms of the disease, and as soon as possible after the possible infection of genitals to them (for casual sex with non-regular sexual partners).
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